Educational reference only - not a pharmacy, not a prescription, not a substitute for the person who holds your chart. Open the docket disclaimer

Uxora Pharma Centres

Docket card · CNS docket

Provigil 200 mg is a wake file, not a study steroid

Last reviewed · 11 min read · Updated

Modafinil 200 mg is the Uxora Provigil lock. For narcolepsy or residual sleepiness in treated OSA, the US label writes 200 mg once in the morning. For shift-work disorder the same 200 mg sits about one hour before the shift, not at a random breakfast.

It is Schedule IV. A US window treats it like a controlled fill, not like a vitamin. Four hundred milligrams has been tolerated in trials; the label does not show a consistent extra benefit over 200 mg.

Read the wake-file memo and the CYP chip. Steroidal contraceptives can lose punch during treatment and for one month after the last tablet.

Docket card

OnsetWake effect the same duty period if timed
DurationEffective t½ about 15 h after multiple doses
FoodMay delay peak; still a once-daily tablet
AlcoholNot a mixer; judgment and sleep debt remain

01Two hundred milligrams is the wake lock, not a 100 mg split story

Intake: name the sleep diagnosis, the 200 mg clock, and the contraceptive month before anyone talks 'focus.'

Shops advertise Provigil as a 100 mg clever-drug split. Uxora files 200 mg because that is the recommended adult dose on the US label for the three approved sleepiness indications. One-hundred-milligram tablets exist. They are a different count, not this lock.

Modafinil promotes wakefulness. It does not replace CPAP, a sleep opportunity, or a diagnosis. Using it to crush an exam week while sleeping four hours is off-label bravado and a poor reason to skip the rash and psychiatric warnings.

Sofia peer-passes timing first. Morning for narcolepsy and OSA. About one hour before a night shift for SWD. A 200 mg swallow at 22:00 before a day job is how people then ask for a hypnotic. That is a mess this desk will not tidy by mail.

Uxora does not dispense. Schedule IV rules at a US pharmacy are the pharmacist's, not a coupon site's. See the fill band on this card for the sourced 200 mg times thirty row.

Provigil 200 mg tablets beside a wake-shift clock

02Morning narcolepsy versus the shift-work hour

Narcolepsy and OSA residual sleepiness share a morning 200 mg on the label. OSA patients were still supposed to use CPAP in the trials. The tablet is not a permission slip to rack the mask.

Shift-work disorder uses the same milligrams on a different clock: about one hour before the shift starts. If the roster flips, the tablet flips. Leaving it at 08:00 'because that is when I take pills' is how night workers stay wired into the commute home.

Four hundred milligrams as a single daily dose showed up in studies. The label says extra benefit over 200 mg was not consistent. Do not self-raise because a forum swears 400 is the real dose.

Elderly clearance can fall. Severe hepatic impairment needs a lower labeled start (often 100 mg on the product insert). That is a clinician cut, not a reason to buy a splitter and guess.

Table 1. Where the 200 mg tablet actually sits
FileLabel clockWhat not to do
Narcolepsy / OSA200 mg morningSkip CPAP and 'replace' it
Shift-work disorder200 mg ~1 h before shiftTake it at breakfast on a night roster
Exam week, no diagnosisNot a labeled fileDo not borrow a mate's CIV

03Hepatic cuts, elderly levels, and the rash clock

Severe hepatic impairment: the insert cuts the dose. Do not keep 200 mg because 'that is the lock.' The lock is the usual adult labeled dose, not a dare in liver failure.

In a small elderly multiple-dose study, plasma levels ran about twice historical younger values. Comedications muddied the picture. Still, start conversations lower in the very old.

Severe renal failure (CrCl at or below 20 mL/min) did not change parent modafinil much in a single-dose study, but the inactive acid metabolite rose about nine-fold. That is a specialist footnote, not a home adjustment.

Sofia Mendes will not diagnose narcolepsy by email. If a reader only wants a study pill, this card is the wrong genre.

Wake-file lines that stay on the card

  • 200 mg morning - narcolepsy / OSA residual sleepiness
  • 200 mg ~1 h before shift - SWD
  • Backup contraception during use and 1 month after
  • Stop for serious rash or psychiatric break
  • Schedule IV - window rules apply

04What 200 mg will not fix, including a weekend PDE5 plan

Modafinil will not treat obstructive sleep apnea. It will not shorten a fluoxetine washout. It will not make Sildalist 120 safer. Wake drugs and PDE5 combos share only this: both get abused as performance kits.

Alcohol plus a wake tablet is a way to feel capable while impaired. Do not drive on that mix. Portugal emergencies: 112.

Food can delay the peak. For a shift start, a heavy meal right before the tablet can slide the wake effect into the wrong hour. The wake-file memo keeps the clock honest.

Angioedema and multi-organ hypersensitivity are rare and ugly. Fever plus rash plus lymphadenopathy is a hospital story.

ADME slip
AbsorptionOral tablet; food may delay Tmax.
DistributionRacemic mix; R-enantiomer dominates trough at steady state.
MetabolismAmide hydrolysis plus CYP3A4; sulfone metabolite t½ ~40 h.
ExcretionEffective elimination t½ ~15 h after multiple doses; steady state 2-4 days.

05CYP3A4 induction and the contraceptive month after stop

Modafinil is a weak CYP3A4 inducer in a concentration-related way. Steroidal contraceptives, cyclosporine, midazolam, and triazolam can lose exposure. Ethinyl estradiol AUC fell about 18 percent in a labeled interaction study at 200 then 400 mg.

The practical line: use a backup or a different contraceptive method while taking Provigil and for one month after the last tablet. That month is easy to forget when someone 'only needed it for a night-shift month.'

Modafinil also inhibits CYP2C19. Diazepam, phenytoin, and propranolol can rise. In CYP2D6-poor metabolizers, some SSRIs and tricyclics that lean on 2C19 as a backup path can rise too. If fluoxetine is already on the chart, the pair needs a named owner.

The CYP chip memo is the short list. Carbamazepine, phenobarbital, and rifampin can push the other way and flatten modafinil.

06Who should not treat 200 mg as a focus vitamin

Left-ventricular hypertrophy, mitral-valve prolapse, and recent infarction histories show up as caution piles on wake-stimulant counselling. This docket will not clear a heart. Chest pain after a 200 mg start is 112, not a 'modafinil buzz.'

Severe hepatic impairment needs a labeled cut, often 100 mg on the insert. The Uxora lock stays 200 mg for the usual adult file. Liver failure is not the usual adult file.

Pregnancy data are messy. The contraceptive month exists because steroidal methods can fail. Wanting a pregnancy is a stop-and-plan, not a 'keep 200 and hope.' The CYP chip is the backup sentence.

Kids under 17 are not a home 200 mg project. This card is adult labeled sleepiness.

A borrowed CIV strip for an exam is theft of a controlled tablet plus every warning on this page. We will not bless one night.

07Schedule IV at the window, and the cash row we will quote

Provigil is Schedule IV. Pharmacists can refuse a sketchy out-of-state script. Coupon acceptance varies. That is not this desk being difficult. It is controlled-substance law.

The Uxora lock is generic modafinil 200 mg, thirty tablets. We quote the sourced GoodRx band on that count. We do not invent a 100 mg split price to look cheaper.

Serious rash, including Stevens-Johnson syndrome, has occurred. Stop for blistering, mucosal lesions, or a spreading fever-rash. Psychiatric reactions (mania, hallucinations, suicidal thinking) are labeled. A 'smart drug' culture does not delete them.

GoodRx average retail$881.37
GoodRx coupon print$27.70

Generic modafinil 200 mg x 30, GoodRx Provigil table, 23 June 2026.

Generic modafinil 200 mg, thirty tablets, the Uxora Provigil lock, August 2026. GoodRx lists 200 mg x 30 at $881.37 average retail and $27.70 with a coupon (23 June 2026). Schedule IV - coupon acceptance varies by pharmacist. One-hundred-milligram splits are a different count. Uxora does not dispense.

08Psychiatric breaks and rash clocks that shops skip

Mania, hallucinations, and suicidal thinking are labeled. A 'smart drug' culture treats them as rare enough to ignore. A bipolar history is a specialist conversation before the first 200 mg, not a yes from a cart. If mood is already climbing in week one, that is urgent psychiatry, not a split to 100 mg.

Serious rash including Stevens-Johnson syndrome has occurred. Blistering, mucosal lesions, or a spreading fever-rash are stops. Do not finish a 30-count because the lock said 200 mg is the real dose. Multi-organ hypersensitivity (fever, rash, nodes, odd labs) is a hospital story.

Anxiety and insomnia can be the tablet doing exactly what a poorly timed 200 mg does: wake at the wrong hour. Move the clock with the roster before anyone adds a hypnotic from a drawer. See the wake-file memo.

Headache, nausea, and dry mouth are the ordinary cluster. They are not a reason to double to 400 mg. The label already said extra benefit at 400 was not consistent.

If a reader also holds fluoxetine 10 mg, name the pair on both desks. CYP2C19 inhibition plus a long SSRI tail is a monitoring story, not an energy patch for week-one SSRI fatigue.

09Keep 200 mg tied to a sleep diagnosis

Provigil 200 mg is a labeled wake dose. It is a controlled tablet with a contraceptive footnote and a rash warning. It is not a harmless focus candy and not a partner for an export PDE5 stack.

Change the clock or the milligrams only with the clinician who owns the sleep file. The disclaimer is the last word on what this desk is not.

Pencil the indication on the blister. Morning for narcolepsy or residual OSA sleepiness. About one hour before the shift for SWD. Mixed months follow the duty.

A second 200 mg at midnight is an amateur 400. The label did not show a consistent extra benefit at 400 mg.

OSA trials kept CPAP. The tablet is leftover wake, not a mask replacement.

Backup contraception through one month after the last tablet. Ethinyl estradiol AUC fell about 18 percent in the labeled interaction study.

Cyclosporine troughs can fall. Transplant wants the start date today.

Serious rash and psychiatric breaks are stops. A night-shift culture does not delete them.

Severe hepatic impairment needs a cut, often 100 mg. The lock is the usual adult file, not liver failure.

Borrowed CIV for an exam is not a diagnosis. We will not bless one night.

Fluoxetine plus 200 mg needs named owners. Not an automatic ban. Not a DIY energy fix.

Sofia files the wake card. She does not write a Schedule IV refill.

Sixteen-hour shifts do not write a home 400 mg. The label already spoke to that dose.

Implants, pills, patches, and rings can fail during treatment and for one month after stop.

Anesthesia needs the 200 mg on the list. Midazolam and triazolam can lose exposure.

A weaker week is not a license to double. Named owners, not a forum climb.

The 200 mg morning lock stays unless the sleep clinic writes another clock. A late tablet writes insomnia and does not write a second diagnosis.

Shift-work disorder still uses 200 mg about one hour before the night start. That is not a license to stack a morning 200 on the same calendar day without the clinic.

Schedule IV is not a casual refill. Lost strips still get a new named owner, not a second cart from another shop.

Psychiatric history belongs on the first consult. Irritability and mania flags are stops, not reasons to add a second stimulant at home.

Hepatic impairment can need a lower start. Do not invent that milligram from a comment. The sleep clinic writes it.

This docket will not quote a dollar. A 200 mg tablet is a clock and a method warning, not a sale.

A missed morning 200 mg is usually a skip, not a 4 p.m. makeup. Late tablets write late nights.

Narcolepsy and OSA share the morning lock on this site. Shift-work disorder uses 200 mg about one hour before the night start. Those clocks do not stack on one calendar day without the clinic.

Schedule IV means lost strips still need a named owner. A second shop cart is not a refill and this docket will not invent a dollar for a replacement.

Psychiatric history belongs on the first consult. Irritability, mania flags, and new aggression are stops, not reasons to add a home stimulant.

Severe hepatic impairment can need a lower start. This desk will not invent that milligram. The sleep clinic writes it and keeps the 200 mg lock unless they move it.

Ethinyl estradiol exposure can fall about 18 percent. Backup through treatment and one month after the last 200 mg is the stamp. This docket will not pick the method.

Midazolam, triazolam, and some transplant drugs can lose punch. Put the wake tablet on every pre-op and clinic list. A clean hour at the dentist is not a reason to hide 200 mg.

Auto-induction talk at week six is a clinic question. It is not a home climb to 400 mg. Extra benefit at 400 was not consistent on the label.

This Porto file stays prescribed-online in the SERP sense: a licensed clinician where you live, then a pharmacy. Uxora stops at the card. Sofia Mendes peer-passes. She does not roster your shift from Cedofeita 455.

[email protected] can flag a wrong clock on this page. It cannot become an e-script for 200 mg.

Sources

  1. DailyMed PROVIGIL (modafinil) tablet label
  2. Label: 200 mg morning (narcolepsy/OSA); 200 mg ~1 h before shift (SWD); CIV; t½ ~15 h.
  3. Label: steroidal contraceptives plus one month after stop; CYP3A4 induction; CYP2C19 inhibition.
  4. Ethinyl estradiol interaction: mean AUC0-24 down ~18% in the labeled study.

Checked against the current label and reviewed by Dr. Sofia Mendes. See Intake, Markup, Peer-pass, File.

Modafinil 4.7 / 5 from 2142 reader ratings

Docket thread

Docket thread for modafinil 200 mg. This is not a script. Chest pain, severe rash, or a psychiatric break: 112 in Portugal.

Celso Quinta, hepatic 200 MELD is ugly. Clinic still wrote 200 because Uxora locks 200.

Desk reply

The lock is the usual adult labeled dose. Severe hepatic impairment is a cut on the insert, often 100 mg. Show the clinic the liver chapter, not our SERP title.

Bento Semedo, 16-hour shift Double 200 because the shift is sixteen hours?

Desk reply

Not from this docket. Extra benefit at 400 mg was not consistent on the label. A longer shift is a roster problem. Call the sleep clinic.

Norberto Paço, wine after a late shift One glass to come down. Fine?

Desk reply

Alcohol plus a wake tablet is a bad judgment mix. If you still need a drink to sleep, the clock or the diagnosis is wrong. Do not drive. Do not add a hypnotic from a drawer.

Rosa Quinta, auto-induction Troughs felt weaker at week six. Take 400?

Desk reply

Small auto-induction signals exist and are inconsistent. Do not self-raise. Sleep clinic owns any change.

Válter Semedo, mitral note Old echo said mitral-valve prolapse. Sleepy on nights. Start 200?

Desk reply

Not from this thread. Cardiac cautions on wake drugs are a clinician look, not a cart. Chest pain after a first tablet is 112, not a forum buzz.

Feliciano Brás, night nurse I take 200 mg at 08:00 even on nights because I forget otherwise. Fix the habit or the dose?

Desk reply

Fix the clock. Shift-work labeling is about one hour before the shift, not a breakfast ritual. A morning tablet on a night roster is how people drive home still lit. The milligrams can stay 200 if the diagnosis is SWD. The hour has to move. See the wake-file memo.

Quirino Bastão, coupon refused GoodRx number on your card, pharmacy said no. Did you invent it?

Desk reply

The cash band is a sourced national print for 200 mg times thirty, dated on the fill caption. Schedule IV desks can refuse a coupon. That is the window, not a fake dollar on our side. Ask them to price the NDC on the script.

Isaura Crasto, Prozac 10 already Psychiatry added fluoxetine. Sleep clinic wants to keep 200 mg. Dangerous?

Desk reply

Not an automatic ban, but not a home stack. Modafinil can inhibit CYP2C19. In 2D6-poor metabolizers some SSRI levels can rise. Both clinicians need the same list. Read the fluoxetine docket for the long tail, not for a DIY energy fix.

Hortênsia Paço, fever rash Day twelve, rash and a fever. Finish the thirty because I paid?

Desk reply

Stop. Fever plus rash can be hypersensitivity. Paid is not a reason to finish a CIV bottle through a labeled serious-skin warning.

Rosa Brás, wanted pregnancy We are trying. I am on 200 for nights. Stop today?

Desk reply

Call the sleep and obstetric pair today. Steroidal methods can already be weaker, and wanting a pregnancy is a plan, not a hope. Backup math on the CYP chip is for people who do not want a pregnancy.

Leandro Furtado, blistering lip Mouth sores on day nine. Keep going because 200 is 'the real dose'?

Desk reply

Stop and get seen. Serious rash including SJS is labeled. Mucosal lesions are not a 'push through the start.' Do not restart because a shop said 200 mg is always tolerated.

Horácio Semedo, cyclosporine trough Transplant team saw a falling level after a wake tablet started. Related?

Desk reply

It can be. Modafinil induces CYP3A4 and can lower cyclosporine. Call the transplant desk today. Do not adjust either drug from a forum. Bring the start date and the 200 mg strength.

Palmira Guedes, ethinyl estradiol pill Do I need an IUD the day I start Provigil?

Desk reply

You need a plan the day you start, and it lasts through one month after you stop. Steroidal pills, patches, rings, and implants can lose effect. The labeled study showed an 18 percent drop in ethinyl estradiol AUC at the higher interaction dose. Pick the backup with your clinician. The CYP chip is the short warning.

Américo Távora, exam month No narcolepsy. Can I still get 200 mg prescribed online as a study aid?

Desk reply

This site does not prescribe. Off-label cognitive use is not the labeled file. Schedule IV plus rash and psychiatric warnings still apply if someone else writes it. Do not borrow a strip. Do not stack it with a leftover Sildalist as a performance kit.

Teolinda Crasto, desk close Sentence to keep.

Desk reply

Provigil 200 mg is a timed wake dose for labeled sleepiness. Backup contraception through one month after stop. Rash and psychiatric flags are stops. Mail [email protected] about wording, not about a CIV refill.

Raquel Mondego, mania history Old bipolar file. Sleepy on nights. Safe 200?

Desk reply

Psychiatric reactions are labeled. A bipolar history is a specialist conversation, not a yes from Porto. Do not start from a cart. If you already started and mood is climbing, that is urgent psychiatry, not a dose-split idea.

Benedita Lobo, CPAP slacker If 200 mg keeps me awake, can I skip the mask?

Desk reply

No. OSA trials kept CPAP on. The tablet treats residual sleepiness, not the airway. Skipping the mask and swallowing Provigil is a miss on both files.

Lidia Paço, implant I have an implant. Still need backup on 200 mg?

Desk reply

Steroidal methods including implants can lose punch. Plan backup through one month after stop. This desk will not pick your method.

Marília Quinta, 100 mg split idea Your lock is 200. My script is 100 twice. Did Uxora get the label wrong?

Desk reply

The recommended labeled dose for the three indications is 200 mg once daily, timed as above. Prescribers sometimes split. That is their chart. Our SERP lock and cash band stay on 200 mg times thirty. We will not invent a 100 mg coupon to match a split.

Ofélia Rijo, Zanaflex for spasm Physio added tizanidine 4 mg. I take Provigil for nights. Sedation vs wake?

Desk reply

Opposite directions on the same day need a named plan. Tizanidine has an absolute CYP1A2 wall with fluvoxamine and ciprofloxacin. Modafinil is not that wall, but stacked sedation and hypotension still happen if the spasm tablet sits near a drive. Open the tizanidine docket before the next night shift.

Celso Brás, midazolam Anesthesia next week. Tell them about 200 mg?

Desk reply

Yes. Modafinil can induce CYP3A4 and lower midazolam. Put the wake tablet on the list today.

Quim Lage, missed morning Missed the 200 mg at 7. Take it at 4 p.m.?

Desk reply

A 4 p.m. 200 mg is a late clock and often writes insomnia. Skip and resume the next morning unless the sleep clinic wrote a shift-work hour. Do not add a second 200 to make up.

Gilberto Semedo, 400 mg forum Trials used 400. Why do you stall at 200?

Desk reply

Because the label says 400 was tolerated but did not consistently beat 200. Forum escalation is not a titration protocol. If a sleep physician raises, they own it.