01Day one is when the 500 mg load hits
People wait for palpitations on day four and call that the QT day. The risk conversation belongs before tablet one.
Known long QT, prior torsades, bradycardia, uncompensated heart failure, uncorrected low potassium or magnesium: say them out loud at the window.
This memo does not read your ECG. It stops a silent start on a piled chart.

02What to do if the faint already happened
Stop. Urgent care. Bring the blister and the home med list. Do not take the next 250 to 'finish the cheap pack.'
Course-seal said empty the blister. That rule yields to a rhythm event.
03Thirty seconds at the window before the 500 mg load
Any rhythm drugs. Any faint. Last potassium or magnesium. Any family long QT. If the answer stalls, the load can wait an hour for a clinician. Day one is when 500 mg hits, not day five.
Class IA and III antiarrhythmics - quinidine, procainamide, dofetilide, amiodarone, sotalol - sit in the higher-risk pile. A walk-in Z-Pak plus home amiodarone is the miss this flag exists for. Do not take the 500 until both files are seen.
Uncorrected hypokalemia or hypomagnesemia is on the FDA list. Starting tonight and replacing K later is not a plan. Ask them to see the number first.
Observational work flagged a short-term rise in cardiovascular death versus some other antibacterials. That is a prescriber benefit-risk line. It is not a leftover excuse and not a reason to skip a needed course without asking.
Faint, chest pain, or collapse after a tablet: stop. Urgent care. Bring the blister and the home list. Do not take the next 250 to finish a cheap pack. Course-seal yields to a rhythm event.
Do not freelance a sotalol hold to 'make the Z-Pak safer.' Skipping an antiarrhythmic is its own risk. Call the rhythm desk.
An athletic low pulse is not automatically the labeled bradycardia pile. Still mention it if a QT drug or low K is also on the list.
Cipro plus tizanidine is a different wall. Do not refuse a Z-Pak because someone said all heart-adjacent drugs pile. Name the INNs. ACE cough on lisinopril is also not this flag.
Mail [email protected] if course-seal ever tells people to ignore faint. That is a bug.
04Drugs that make the flag louder
Class IA and III antiarrhythmics: quinidine, procainamide, dofetilide, amiodarone, sotalol.
Other QT drugs add. A walk-in Z-Pak plus a home amiodarone is the miss this chip exists for.
Observational work flagged a short-term rise in cardiovascular death versus some other antibacterials. That is a prescriber benefit-risk line, not a leftover excuse and not a reason to skip a needed course without asking.
| Flag | Example | Desk |
|---|---|---|
| Rhythm history | Long QT, prior TdP | Ask before 500 mg |
| Electrolytes | Low K or Mg | Correct / delay |
| QT drugs | Amiodarone, sotalol | Do not silent-start |
05Do not confuse this flag with the cipro-tizanidine wall
Ciprofloxacin plus tizanidine is a 10-fold CYP story. Azithromycin plus tizanidine is not that contraindication. QT plus sedation can still look ugly. Name both INNs.
ACE cough on lisinopril is not a QT story. Do not skip a Z-Pak because someone said 'all heart drugs pile.'
06A thirty-second window question
Any rhythm drugs, any faint, last potassium, any family long QT? If the answer stalls, the 500 mg can wait an hour for a clinician.
Mail [email protected] if our course-seal ever tells people to ignore faint.
QT-flag pocket lines
- Ask before the load
- Low K/Mg matters
- Amiodarone is a pile
- Faint stops the pack
07Keep the flag on day one
Course math: seal. Long file: docket.
Disclaimer. Sofia does not clear your QT from Porto.
Ask before the 500 mg load: rhythm drugs, faint, last potassium or magnesium, family long QT. If the answer stalls, the load can wait an hour.
Quinidine, procainamide, dofetilide, amiodarone, and sotalol sit in the higher-risk pile. A walk-in Z-Pak plus home amiodarone is the miss this flag exists for.
Uncorrected hypokalemia or hypomagnesemia is on the FDA list. Starting tonight and replacing K later is not a plan.
The 2013 communication told clinicians to think about torsades before azithromycin, not after a faint on day four.
Observational work flagged a short-term rise in cardiovascular death versus some other antibacterials. Benefit-risk for the prescriber, not a leftover excuse.
Faint, chest pain, or collapse: stop. Bring the blister and the home list. Do not take the next 250 to finish a cheap pack.
Course-seal yields to a rhythm event. Empty is for an ordinary bacterial course, not for a grey-out.
Do not freelance a sotalol hold to make the Z-Pak safer. Skipping an antiarrhythmic is its own risk.
An athletic low pulse is not automatically the labeled bradycardia pile. Still mention it if a QT drug or low K is also on the list.
Cipro plus tizanidine is a different wall. ACE cough on lisinopril is not this flag. Name the INNs.
Myasthenia and severe liver disease are other stops that also beat a cheap pack story.
This memo does not read your ECG. It stops a silent start on a piled chart.
Mail the desk if course-seal ever tells people to ignore faint. That is a bug.
Sofia flags the question. She does not clear your QT from Porto.
2013 is not expired. The QT communication still stamps this pack.
A watch ring is not a 12-lead. High-risk hearts still need a clinician.
Citalopram plus azithromycin is a stack question, not a cough upgrade.
Methadone plus a Z-Pak is a clinic call before day one.
Last month's low potassium is a reason to ask, not a leftover start.
Family sudden death belongs on the history before a macrolide.
Skipping the 500 mg load is not a homemade QT diet. It is an unlabeled course.
Palpitations on day two are a call. Leftovers are not the plan.
Other QT drugs and low magnesium sit on the same list.
This flag will not quote a dollar. Six by 250 is the pack, not a sale.
Sofia Mendes peer-passes the QT chip. She does not read your watch.
If you faint, you do not email this desk. You use emergency services.
The 2013 FDA QT communication still stamps this pack. A five-day course does not expire the warning. High-risk hearts need the clinician before the first 500 mg.
Citalopram, methadone, low potassium, and low magnesium sit on the same list. Do not add a Z-Pak from a drawer onto another QT story.
Family sudden death belongs on the history before a macrolide. This inbox is not that clinic.
Skipping the 500 mg load is not a homemade QT diet. A different regimen needs a named owner. The labeled Z-Pak is 500 then four days of 250.
Palpitations on day two are a call. Two leftover tablets are not a finish-the-myth note.
A ring or watch is not an assay. This flag will not bless a home ECG.
Myasthenia and pregnancy still sit on the first call even when the QT chip is the headline.
This flag will not quote a dollar. Six by 250 is the pack, not a sale.
Sofia Mendes peer-passes the QT chip. She does not read your watch from Porto.
If you faint, you do not email. You use emergency services. [email protected] can correct a wrong year on this page. It cannot clear a flutter.
The 2013 FDA QT communication still stamps this five-day pack. High-risk hearts, other QT drugs, low potassium, and family sudden death belong on the call before the first 500 mg.
A consumer watch is not a 12-lead. Palpitations or flutter are a stop-and-call. Fainting is emergency services. Leftovers are not the plan.
Citalopram plus a Z-Pak is a stack question. Myasthenia and pregnancy still sit on the first call even when QT is the headline.
This flag will not quote a dollar. Six by 250 is the pack. Sofia Mendes does not read your watch from Porto.
[email protected] can correct a wrong year on this page. It cannot clear a flutter.
Prescribed-online still means a licensed clinician where you live. This inbox is not cardiology and not an ECG desk.
Family sudden death, methadone, citalopram, and last month's low potassium all belong on the call before a Z-Pak. The 2013 communication did not expire.
Skipping the 500 mg load is not a homemade QT diet. Palpitations on day two are a stop-and-call. Two leftover 250s are not a finish plan.
This flag will not quote a dollar. Sofia Mendes does not read a consumer watch. High-risk hearts still need a clinician before day one.
A five-day course does not erase 2013. High-risk hearts still ask before the first 500 mg. A consumer ring is not an assay.
This QT flag will not quote a dollar. Leftovers after a flutter are not a finish plan. Sofia Mendes does not clear a home ECG from Porto.
Myasthenia still sits on the first call even when the QT chip is the headline. Do not start a leftover pack to test a watch ring.
Sources
- FDA 2013 azithromycin QT / TdP communication.
- Zithromax PI 5.4-5.5: QT, TdP, observational CV death signal.
Checked against the current label and reviewed by Dr. Sofia Mendes. See Intake, Markup, Peer-pass, File.